Guoqiang Yu, Ph.D.

Center for Biomedical Engineering
Wenner-Gren Research Lab
University of Kentucky
Lexington, KY 40506-0070

Tel: 859-257-9110 Fax: 859-257-1856

guoqiang.yu@uky.edu

EDUCATION

Dept. of Biomedical Engineering and Instrumentation, Tianjin University of China, Tianjin, China

· Ph.D. of Biomedical Engineering -2000

RESEARCH EXPERIENCE

Center for Biomedical Engineering, University of Kentucky, Lexington, KY, USA

· Assistant Professor 2007-

Dept. of Physics & Astronomy, University of Pennsylvania, Philadelphia, USA

· Research Assistant Professor 2006-2007

· Senior Research Investigator 2004-2006

· Research Associate 2002-2004

• Postdoctoral Fellow 2001-2002

Physikalisch-Technische Bundesanstalt (PTB), Braunschweig, Germany

· Research Scientist 1999-2001

TEACHING EXPERIENCE

Center for Biomedical Engineering, University of Kentucky, Lexington, KY, USA

· BME 501: Foundations of Biomedical Engineering

· BME 530: Biomedical Instrumentation

GRANT SUPPORT

Active

· America Heart Association (AHA) BGIA #2350015 7/1/2009-6/30/2011

A Portable Optical Flow-Oximeter for Assessment of Cerebral Hemodynamics and Metabolism during Obstructive Sleep Apnea (OSA)

To develop a high-throughput, portable, and easy-to-use optical device for simultaneous monitoring multiple cerebral physiological parameters (e.g., cerebral blood flow, oxygenation, and oxygen metabolism) during sleep in patients with obstructive sleep apnea (OSA).

Role: PI

· R21-PA-08-162 (NIH) 9/15/2009-8/31/2011

Contribution of Altered Muscle Hemodynamics to Fatigability in Older Persons with and without Fibromyalgia

To identify defects in muscle physiology of older fibromyalgia (FM) patients, as well as older healthy but fatigable individuals, which may contribute to this symptom.

Role: Co-Investigator

Finished

· R21-HL083225 (NIH) 2/15/2006-1/30/2010

Assessment of Muscle Vascular Disease with Diffuse Light

To provide multiple hemodynamic parameters for evaluation of microcirculation and tissue metabolism in the patients with varying degrees of claudication and chronic limb ischemia (CCLI).

Role: PI

· America Heart Association BGIA #0665446U 7/1/2006-6/30/2009

Diffuse Optical Mapping Of Blood Flow, Oxygenation, and Metabolism in Ischemic Skeletal Muscle

To develop and utilize noninvasive hybrid optical instruments for simultaneous and continuous regional mapping of blood flow, oxygenation and metabolism in ischemic skeletal muscles. These measurements will provide information for classification and localization of ischemic tissue and for the evaluation of revascularization outcomes.

Role: PI

· New Investigator Award (W81XWH-04-1-0006) 2/1/2004-1/31/2007

Department of Defense (DOD)

Real-time Diffuse Optical Measurement for In-vivo PDT Dosimetry of Human Prostate

To develop a new way to measure photosensitizer concentration, blood oxygen, and blood flow in cancer tissues during photodynamic therapy (PDT) in order to improve treatment effect.

Role: PI

· R01-HL-077699-01 (NIH) 9/1/2004-8/31/2008

Diffuse Light Imaging of Flow, Oxygen & Brain Metabolism

To construct and use a versatile all-optical imaging probe for measurement of blood oxygenation, blood flow, the cerebral metabolic rate for oxygen extraction (CMRO₂) in human brain.

Role: Co-Investigator

· NIH-R21-EB007610-01 (NIH) 8/1/2007-7/31/2009

Absolute Measurement of Cerebral Blood Flow Using Diffuse Optics

To develop and validate optical methods for non-invasive measurement of absolute cerebral blood flow.

Role: Co-Investigator

· Upenn Abramson Cancer Center Collaborative Pilot Project 7/1/2005-6/30/2006

Real-time Diffuse Optical Measurement for Dosimetry During Photofrin Pleural Photodynamic Therapy

To develop a new way to measure photosensitizer concentration, blood oxygen, and blood flow in pleural tissues during photodynamic therapy.

Role: Co-Investigator

PATENT (pending): United States Patent Application No. 11/106390

Title: Optical Measurement of Tissue Blood Flow Hemodynamics and Oxygenation

AWARDS AND HONORS

· Section co-chair, Multimodal Biomedical Imaging V, SPIE Photonics West (San Francisco, CA, Jan. 2010)

• One of the symposium organizers and speakers in 2010 ACSM Annual Meeting, entitled "Discussions on How to Use NIRS to Evaluate Skeletal Muscle”, American College of Sports and Medicine (Baltimore, MA, June 2010)
• NIH study section/site reviewer for RC3 and R43 ARRA grant applications (Washington DC, Nov. 2009)
• Section co-chair, 11^th World Congress of the International Photodynamic Association (IPA, Shanghai, China, March 2007)

· Second Place Winner (out of 45+ international competitors) of Young Investigators Awards Competition in 17^th Annual Meeting of the Society of Vascular Medicine and Biology (SVMB, Philadelphia, PA, June 2006)

· Best Poster Award (out of 80+ posters) in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, Dec. 2004)

· Second Place Winner (out of 45+ international competitors) of Young Investigators Awards Competition in 15^th annual meeting of the Society of Vascular Medicine and Biology (SVMB, Anaheim, CA, June 2004)

MANUSCRIPT REFEREE FOR JOURNALS

Journal of Biomedical Optics, Optics Letters, Applied Optics, Optics Express, Journal of Electronic Imaging, Medical Physics, Journal of Neoplasia, Transactions on Medical Imaging (IEEE), Archives of Physical Medicine and Rehabilitation, CardioVscular & Interventional Radiology, BioMedical Engineering OnLine, Journal of Applied Physiology, Journal of Innovative Optical Health Sciences, Journal of Modern Optics, Optical Engineering

PROFESSIONAL MEMBERSHIPS

Optical Society of American (OSA), The International Society for Optical Engineering (SPIE), American Society of Photobiology (ASP), Society of Vascular Medicine and Biology (SVMB), American College of Sports Medicine (ACSM), Biomedical Engineering Society

RECENT PUBLICATIONS/PRESENTATIONS (1998-):

Peer-reviewed Articles in Journals:

· Y. Shang, Y. Zhao, R. Cheng, L. Dong, D. Irwin, and G. Yu, “Portable optical tissue flow oximeter based on diffuse correlation spectroscopy,” Opt Lett 34(22), 3556-3558 (2009)

• T. M. Busch, X. Xing, G. Yu, A. G. Yodh, E. P. Wileyto, H. W. Wang, T. Durduran, T. C. Zhu, K. K.H. Wang, “Fluence rate-dependent intratumor heterogeneity in physiologic and cytotoxic responses to photofrin photodynamic therapy,” Photochem Photobiol Sci. 8: advance online (2009)
• T. Durduran, C. Zhou, E. M. Buckley, M. N. Kim, G. Yu, R. Choe, W. J. Gaynor, T. L. Spray, S. M. Durning, S. E. Mason, L. M. Montenegro, S. C. Nicolson, R. A. Zimmerman, M. E. Putt, J. J. Wang, J. H. Greenberg, J. A. Detre, A. G. Yodh, and D. J. Licht. “Optical measurement of cerebral hemodynamics and oxygen metabolism in neonates with congenital heart defects,” J Biomed Opt, accepted (2009)
• M. N. Kim, T. Durduran, S. Frangos, B. L. Edlow, E. M. Buckley, H. E. Moss, C. Zhou, G. Yu, R. Choe, E. Maloney-Wilensky, R. L. Wolf, M. S. Grady, J. H. Greenberg, J. M. Levine, A. G. Yodh, J. A. Detre, and W. A. Kofke, "Noninvasive measurement of Ccerebral blood flow and blood oxygenation using near-infrared and diffuse correlation spectroscopies in critically brain-injured adults," Neurocrit Care: advance online (2009)
• C. Zhou, S. A. Eucker, T. Durduran, G. Yu, J. Ralston, S. H. Friess, R. N. Ichord, S. S. Margulies, and A. G. Yodh, “Diffuse optical monitoring of hemodynamic changes in piglet brain with closed head injury,” J Biomed Opt 14(3):034015 (2009)

· T. Durduran, C. Zhou, L. E. Brian, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, A. G. Yodh, and J. A. Detre, "Transcranial optical monitoring of cerebral blood flow and hemoglobin concentration in acute stroke patients during positional interventions," Annals of Neurology, Optics Express 17(5):3884-3902 (2009)

· M. Buckley, N. M. Cook, T. Durduran, M. N. Kim, C. Zhou, R. Choe, G. Yu, S. Schultz, C. M. Sehgal, D. J. Licht, P. H. Arger, M. E. Putt, H. H. Hurt, and A. G. Yodh. “Cerebral hemodynamics in preterm infants during positional intervention measured with diffuse correlation spectroscopy and transcranial doppler ultrasound,” Optics Express, 17(15):12571-12581 (2009)

· C. Zhou, T. Shimazu, T. Durduran, J. Luckl, D. Y. Kimberg, G. Yu, X. H. Chen, J. A. Detre, A. G. Yodh and J. H. Greenberg, "Acute functional recovery of cerebral blood flow after forebrain ischemia in rat," J Cereb Blood Flow Metab 28(7), 1275-1284 (2008)

· G. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. A. Detre, A. G. Yodh, “Diffuse Correlation Spectroscopy for Muscle Blood Flow: Validation with Arterial-Spin-Labeling Perfusion MRI,” Optics Express, 15:1064-1075, 2007

· U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee and A. G. Yodh, "Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies," Optics Express 15(23), 15507-15516 (2007)

· C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg and A. G. Yodh, "Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy," J Biomed Opt 12(5), 051903 (2007)

· C. Zhou, G. Yu, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh and T. Durduran, "Diffuse optical correlation tomography of cerebral blood flow during cortical spreading depression in rat brain," Optics Express 24(3), 1125-1144 (2006)

· G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn and A. G. Yodh, "Real-time in situ monitoring of human prostate photodynamic therapy with diffuse light," Photochem Photobiol 82(5), 1279-1284 (2006)

· U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance and A. G. Yodh, "Noninvasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study," J Biomed Opt 11(6), 064021 (2006)

· K. L. Du, R. Mick, T. M. Busch, T. C. Zhu, J. C. Finlay, G. Yu, A. G. Yodh, S. B. Malkowicz, D. Smith, R. Whittington, D. Stripp and S. M. Hahn, "Preliminary results of interstitial motexafin lutetium-mediated PDT for prostate cancer," Lasers Surg Med 38(5), 427-434 (2006)

· G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, H. M. Saunders, C. M. Sehgal, E. Glatstein, A. G. Yodh and T. M. Busch, "Noninvasive monitoring of murine tumor blood flow during and after photodynamic therapy provides early assessment of therapeutic efficacy," Clin Cancer Res 11(9), 3543-3552 (2005)

· G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, 3rd and A. G. Yodh, "Time-dependent blood flow and oxygenation in human skeletal muscles measured with noninvasive near-infrared diffuse optical spectroscopies," J Biomed Opt 10(2), 024027 (2005)

· T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki and A. G. Yodh, "Diffuse optical measurement of blood flow in breast tumors," Opt Lett 30(21), 2915-2917 (2005)

· T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou and A. G. Yodh, "Diffuse optical measurement of blood flow, blood oxygenation, and metabolism in a human brain during sensorimotor cortex activation," Opt Lett 29(15), 1766-1768 (2004)

· T. Durduran, M. G. Burnett, G. Yu, C. Zhou, D. Furuya, A. G. Yodh, J. A. Detre and J. H. Greenberg, "Spatiotemporal quantification of cerebral blood flow during functional activation in rat somatosensory cortex using laser-speckle flowmetry," J Cereb Blood Flow Metab 24(5), 518-525 (2004)

· G. Yu, T. Durduran, D. Furuya, J. H. Greenberg and A. G. Yodh, "Frequency-domain multiplexing system for in vivo diffuse light measurements of rapid cerebral hemodynamics," Appl Opt 42(16), 2931-2939 (2003)

· R. Choe, T. Durduran, G. Yu, M. J. Nijland, B. Chance, A. G. Yodh and N. Ramanujam, "Transabdominal near infrared oximetry of hypoxic stress in fetal sheep brain in utero," Proc Natl Acad Sci U S A 100(22), 12950-12954 (2003)

· G. Yu, Y. Y. Li, Q. and X. Hu, "Dynamics models in sclerostomy and in sclerostomy with Iridotomy," Chinese Journal of Biomedical Engineering 21(3), 275-281 (2002)

· K. Hasche, K. Herrmann, W. Mirande, R. Deemann, L. Vitushkin, M. Xu and G. Yu, "Calibrated scanning force microscope with capabilities in the subnanometre range," Surface and Interface Analysis 33(2), 71-74 (2002)

· Q. Yu, G. Yu and X. Hu, "Optimization of pulsed CO2 laser sclerostomy," Journal of Tianjin University (Science and Technology) 34(2), 193-197 (2001)

· G. Yu, A. Liu, G. Zhang and X. Hu, "Thermal physical property measurement using plane-heat source with constant heat rate," Journal of Apparatus and Instruments 21(1), 113-115 (2000)

· G. Yu, A. Liu and X. Hu, "Scanning tunneling microscopy (STM) system with atomic micropositioning " Aviation Precision Manufacturing Technology 35(1), 35-37 (1999)

· G. Yu, X. Hu and A. Liu, "Nanometer scale positioning control and nanofabrication," Journal of Tianjin University (Science and Technology) 32(3), 308-311 (1999)

· A. Liu, G. Yu, Y. Yang and X. Hu, "Image reconstruction for scanning tunneling microscopy (STM)," Journal of Chinese Electron Microscopy Society 18(1), 115-118 (1999)

· D. Li and G. Yu, "Multi-channel real-time monitoring system of environmental protecting equipments," Monitoring Technique 18(2), 19-22 (1999)

· X. Hu, G. Yu, A. Liu and Y. Yang, "3D monolithic ultra-micropositioning system," Journal of Chinese Electron Microscopy Society 18(1), 141-144 (1999)

· G. Yu, A. Liu, G. Zhang and X. Hu, "Thermal physical property measurement using hot-line source with constant heat rate.," Aviation Precision Manufacturing Technology 34(6), 39-41 (1998)

· G. Yu and D. Li, "Real-time monitoring of environmental protecting equipments," Electronics and Automation 27(4), 8-11 (1998)

· A. Liu, G. Yu, P. Qi and X. Hu, "Positioning errors of the scanning probe microscopy (SPM) scanner," Aviation Precision Manufacturing Technology 34(4), 33-35 (1998)

Invited Talks in Academic Seminars/Courses/Conferences:

• Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism in Skeletal Muscle, UK Lung Biology Research Group Meeting, University of Kentucky (Lexington, KY, Feb. 2008)

· Near-Infrared Diffuse Optical Technologies for Cancer Research, UK HOBMT Grand Rounds, Markey Cancer Center, University of Kentucky (Lexington, KY, March 2008)

· Diffuse Optical Quantification of Tissue Blood Flow, Oxygenation and Metabolism in Brain and Muscle, UK Neurology Grand Rounds, University of Kentucky (Lexington, KY, March. 2008)

· Diffuse Optical Quantification of Tissue Blood Flow, Oxygenation and Metabolism in Brain and Muscle, UK Pediatrics Research Group Meeting, University of Kentucky (Lexington, KY, Apr. 2008)

· Diffuse Optical Spectroscopy and Tomography of Tissue Hemodynamics, UK Symposia on Advanced Medical Imaging, University of Kentucky (Lexington, KY, June 2008)

· Near-infrared Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation and Metabolism, UK Clinical and Translational course (BSC772), CTS Fall Seminar Serial Grand Rounds, University of Kentucky (Lexington, KY, Aug. 2008).   

• Diffuse Optical Measurements of Prostate Blood Flow and Oxygenation During Interstitial Photodynamic Therapy, in the inaugural IMPaCT (Innovative Minds in Prostate Cancer Today) meeting (Atlanta, GA, Sep., 2007)
• Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Department of Biomedical Engineering, University of Georgia (Athens, GA, Sep., 2007)

• Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Department of Biomedical Engineering, Stony Brook University (Long Island, NY, May, 2007)
• Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Center for Biomedical Engineering, University of Kentucky (Lexington, KA May, 2007)
• Diffuse Optical Measurement of Tissue Blood Flow, Oxygenation, and Metabolism, in the Department of Biomedical Engineering, Wayne State University (Detroit, MI, Sep., 2006)

• Concurrent Optical-MRI Measurement of Limb Blood Flow/Perfusion, in SVMB 17th Annual Meeting (Philadelphia, PA, June, 2006)
• Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation During Photodynamic Therapy, in Wellman Center for Photomedicine, MGH, Harvard Medical School (Boston, MA, May, 2006)
• Assessment of Muscle Vascular Disease with Diffuse Light, in Molecular Beacons – Novel Optical and NMR Approaches to Cancer Study: Detection and Therapy of Cancer (BMB Course #18), (Philadelphia, PA, Nov., 2005)

• Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscles Measured by Noninvasive Near-infrared Diffuse Optical Spectroscopies, in Vascular Surgery Conference, Division of Vascular Surgery, Department of Surgery, University of Pennsylvania (Philadelphia, PA, Nov., 2004)

• Near-Infrared Diffuse Optical Spectroscopies and Arterial-Spin-Labeling MRI of Human Muscle -- Validation and Correlation of Two Complementary and Noninvasive Techniques, in Center for Advanced Magnetic resonance Imaging and Spectroscopy (CAMRIS), Hospital of University of Pennsylvania (Philadelphia, PA, Oct., 2004)

• Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in PDT Seminar, Hospital of University of Pennsylvania (Philadelphia, PA, Sep., 2004)

• Noninvasive Quantification of Oxidative Metabolism in Human Skeletal Muscle Using Hybrid Near-infrared Diffuse Optical Spectroscopies, in SVMB 15th Annual Meeting (Anaheim, CA, June, 2004)

• Noninvasive Quantification of Oxidative Metabolism in Human Skeletal Muscle Using Hybrid Near-infrared Diffuse Optical Spectroscopies, in Britton Chance Lab Seminar, University of Pennsylvania (Philadelphia, PA, May, 2004)

Selected Presentations/Publications in Conferences/Proceedings:

-- 2010 --

• G. Yu, Y. Shang, Y. Zhao, R. Cheng, L. Dong, and D. Irwin, “Portable Optical Tissue Flow Oximeter Based on Diffuse Correlation Spectroscopy”, SPIE Photonics West (Oral Presentation), San Francisco, CA, 2010
• Y. Shang, Y. Zhao, R. Cheng, L. Dong, S. P. Saha, and G. Yu “Intraoperative Assessment of Acute Revascularization Effect on Ischemic Muscle Perfusion”, SPIE Photonics West (Oral Presentation), San Francisco, CA, 2010

· G. Yu, Y Shang, Y. Zhao, R. Cheng, L. Dong, I. Daniel, and S. P. Saha, “Portable Optical Tissue Flow Oximeter for Evaluation of Revascularization Effect on Ischemic Muscle Hemodynamics,” OSA Biomedical Optics (BIOMED), Miami, FL, 2010

· R. Cheng, Y. Shang, D. Kameny, D. Hayes Jr, and G. Yu, “Noninvasive Optical Evaluation of Cerebral Autoregulation in Patients with Obstructive Sleep Apnea,” OSA Biomedical Optics (BIOMED), Miami, FL, 2010

· Y. Shang, R. Cheng, L. Dong, S. P. Saha, and G. Yu, “Diffuse Optical Detection of Cerebral Ischemia During Carotid Endarterectomy,” OSA Biomedical Optics (BIOMED), Miami, FL, 2010

· Y. Shang, Y. Zhao, R. Cheng, L. Dong, D. Irwin, K. R. Swartz, S. S. Salles, and G. Yu, “Diffuse Optical Spectroscopies for Evaluation of Muscle Hemodynamic Enchantments by Electrical Stimulation,” OSA Biomedical Optics (BIOMED), Miami, FL, 2010

-- 2009 --

• Y. Shang, Y. Zhao, R. Cheng, D. Irwin, L. Dong, K. R. Swartz, S. S. Salles, and G. Yu, "Noninvasive Assessment of Muscle Hemodynamic Enhancement by Electrical Stimulation Using Diffuse Optical Spectroscopies," BMES 2009 Annual Scientific Meeting (Oral Presentation), Pittsburgh, PA, 2009
• Y. Zhao, Y. Shang, R. Cheng, L. Dong, S. P. Saha, and G. Yu, "Diffuse Optical Monitoring of Revascularization Effect on Skeletal Muscle Perfusion," BMES 2009 Annual Scientific Meeting (Poster), Pittsburgh, PA, 2009
• R. Cheng, Y. Shang, Y. Zhao, L. Dong, D. Hayes, and G. Yu, "Noninvasive Diffuse Optical Evaluation of Cerebral Autoregulation”, BMES 2009 Annual Scientific Meeting (Poster), Pittsburgh, PA, 2009
• G. Yu, Y. Zhao, Y. Shang, R. Cheng, L. Dong, and S. P. Saha, "Intraoperative Evaluation of Revascularization Effect on Ischemic Muscle Perfusion," 2^nd Photonics and OptoElectronics Meetings (POEM 2009, Oral Presentation), Wuhan, China, 2009
• G. Yu, Y. Shang, Y. Zhao, R. Cheng, D. Irwin, L. Dong, K. R. Swartz, and S. S. Salles, "Diffuse Optical Evaluation of Muscle Hemodynamic Responses to Electrical Stimulation," 2^nd Photonics and OptoElectronics Meetings (POEM 2009, Poster), Wuhan, China, 2009
• Y. Shang, Y. Zhao, R. Cheng, L. Dong, S. P. Sibu, and G. Yu “Intraoperative Assessment of Acute Revascularization Effect on Ischemic Muscle Perfusion”, UK Linda and Jack Gill Heart Institute Cadiovascular Research Day, Poster Section, University of Kentucky, 2009
• Y. Shang, Y. Zhao, R. Cheng, D. Irwin, L. Dong, K. R. Swartz, S. S. Salles, and G. Yu, "Noninvasive Assessment of Muscle Hemodynamic Enhancement by Electrical Stimulation Using Diffuse Optical Spectroscopies," UK Linda and Jack Gill Heart Institute Cadiovascular Research Day, Poster Section, University of Kentucky, 2009
• R. Cheng, Y. Shang, Y. Zhao, L. Dong, D. Hayes, and G. Yu, "Noninvasive Diffuse Optical Evaluation of Cerebral Autoregulation”, UK Linda and Jack Gill Heart Institute Cadiovascular Research Day, Poster Section, University of Kentucky, 2009
• Y. Shang, Y. Zhao, R. Cheng, L. Dong, S. P. Sibu, and G. Yu “Intraoperative Assessment of Acute Revascularization Effect on Ischemic Muscle Perfusion”, Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, Poster Section, University of Kentucky, 2009
• Y. Shang, Y. Zhao, R. Cheng, D. Irwin, L. Dong, K. R. Swartz, S. S. Salles, and G. Yu, "Noninvasive Assessment of Muscle Hemodynamic Enhancement by Electrical Stimulation Using Diffuse Optical Spectroscopies," Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, Poster Section, University of Kentucky, 2009
• R. Cheng, Y. Shang, Y. Zhao, L. Dong, D. Hayes, and G. Yu, "Noninvasive Diffuse Optical Evaluation of Cerebral Autoregulation”, Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, Poster Section, University of Kentucky, 2009
• Buckley E M, Cook N, Durduran T, Kim M, Zhou C, Choe R, G. Yu, Licht D J, Detre J A, Greenberg J H, Hurg H, and Yodh A G. Cerebral hemodynamics of preterm infants during postural intervention measured with diffuse correlation spectroscopy and transcranial doppler ultrasound. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009
• Durduran T, Kim M N, Buckley E M, Choe R, Zhou C, G. Yu, and Yodh A G. Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities. In SPIE Photonics West. San Jose, CA, 2009
• Durduran T, Kim M N, Buckley E M, Zhou C, G. Yu, Choe R, Durning S M, Mason S, Montenegro L M, Nicholson S C, Putt M E, Zimmerman R A, Wang J, Greenberg J H, Detre J A, Yodh A G, and Licht C J. Cerebral oxygen metabolism (cmro2) reactivity to hypercapnia in neonates with severe congenital heart defects measured with diffuse optics. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009
• Edlow B, Kim M N, Durduran T, Buckley E M, Zhou C, G. Yu, Putt M E, Yodh A G, Greenberg J H, and Detre J A. The effect of healthy aging on cerebral and systemic hemodynamic responses to posture change. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009
• Kim M N, Durduran T, Frangos S, Buckley E M, Zhou C, G. Yu, Moss H, Edlow B L, Maloney-Wilensky E, Detre J A, Greenberg J H, Kofke A W, Yodh A G, Grady S M, Wolf R L, and Levine J. Diffuse optical measurements of cerebral blood flow and oxygenation in patients after traumatic brain injury or subarachnoid hemorrhage. In Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside. National Institutes of Health, Bethesda, MD, 2009
• Kim M N, Durduran T, Frangos S, Edlow B L, Buckley E M, Moss H, Zhou C, G. Yu, Choe R, Maloney-Wilensky E, Wolf R L, Woo J H, Grady M S, Greenberg J H, Levine J, Yodh A G, Detre J A, and Kofke W A. Non-invasive measurements of cerebral blood flow with diffuse optics in patients after severe head injury. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009
• Kim M N, Durduran T, Frangos S, Edlow B L, Buckley E M, Moss H, Zhou C, G. Yu, Choe R, Maloney-Wilensky E, Wolf R L, Woo J H, Grady S M, Greenberg J H, Levine J, Detre J A, Kofke W A, and Yodh A G. Measurements of cerebral blood flow and blood oxygenation with diffuse optics in patients after severe brain injury. In European Conferences on Biomedical Optics, OSA. Munich, Germany, 2009
• Zhou C, Euckner S A, Durduran T, G. Yu, Ralston J, Friess S H, Ichord R N, Margulies S S, and Yodh A G. Diffuse optical monitoring of cerebral hemodynamics in piglet with traumatic brain injury. In BRAIN 09, International Society of Cerebral Blood Flow and Metabolism. Chicago, USA, 2009

-- 2008 --

• G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, F. S. Joseph, A. G. Yodh, Diffuse Optical Measurements of Prostate Blood Flow and Oxygenation During Interstitial Photodynamic Therapy, Markey Cancer Research Day, Poster Section (University of Kentucky, Oct. 2008)
• G. Yu, Y. Zhao, D. Mukherjee, S. P. Saha, Diffuse Light Assessment of Peripheral Artery Disease (PAD) and Revascularization, Adult Skeletal Muscle Symposium: Clinical Problems, Molecular Targets, Poster Section (University of Kentucky, Oct. 2008)
• G. Yu, Y. Zhao, D. Mukherjee, S. P. Saha, Diffuse Light Assessment of Peripheral Artery Disease (PAD) and Revascularization, UK Linda and Jack Gill Heart Institute Cadiovascular Research Day, Poster Section (University of Kentucky, Oct. 2008)

· G. Yu, Diffuse Light Assessment of Peripheral Artery Disease (PAD), 3^rd Annual Clinical and Translational Science Spring Conference, Poster Section (University of Kentucky, June 2008)

• G. Yu, C. Ahn, X. Xing, T. Durduran, E. R. Mohler III, F. Erdman, A. G. Yodh, R, Salcido, Heat and Cold on the Back Modulate Blood Flow in Distant Skeletal Muscles, 55th annual meeting of American College of Sports and Medicine (Indianapolis IN, June 2008)
• G. Yu, T. M. Busch, T. Durduran, C. Zhou, X. Xing, T. Zhu, J. C. Finlay, S. B. Malkowicz, S. M. Hahn, A. G. Yodh, Blood Flow Responses to Photodynamic Therapy with Two Photosensitizers: Photofrin and Motexafin Lutetium (MLu), OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)
• X. Xing, E. R. Mohler III, T. Durduran, C. Zhou, G. Lech, A. G. Yodh, G. Yu, Diffuse Light Quantification of Peripheral Artery Disease (PAD), OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)
• D. R. Busch, C. Zhou, G. Yu, R. Choe, T. Durduran, M. A. Rosen, M. D. Schnall, A. G. Yodh, Effects of Compression on Transillumination Measurements of Blood Flow and Chromophore Concentrations in Human Breast Tissue, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)
• E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, A. G. Yodh, Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)
• T. Durduran C. Zhou, B. L. Edlow, G. Yu, R. Choe, M. N. Kim, B. L. Cucchiara, M. E. Putt, Q. Shah, S. E. Kasner, J. H. Greenberg, J. A. Detre, A. G. Yodh, Non-invasive Measurement of Cerebral Autoregulation of Acute Ischemic Stroke Patients with Diffuse Correlation/Wave Spectroscopy, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)
• M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage, OSA Biomedicals Topicals (St Petersburg, FL, Mar. 2008)
• T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, D. J. Licht, Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects, Annual Meeting of the American Neurological Association (Salt Lake City, Utah, Sep. 2008)
• M. N. Kim, T. Durduran B. L. Edlow, C. Zhou, G. Yu, E. M. Buckley, A. G. Yodh, J. H. Greenberg, J. A. Detre, Healthy Aging Alters the Hemodynamic Response to Orthostatic Stress, International Stroke Conference (2008)
• T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, J. A. Detre, Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes, Annual Meeting of the American Neurological Association (Salt Lake City, Utah, Sep. 2008)
• T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, J. A. Detre, Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes, Annual Meeting of the American Neurological Association (Salt Lake City, Utah, Sep. 2008)
• M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, J. Levine, Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage, Neurocritical Care Society Annual Meeting (Miami, FL, 2008)

-- 2007 --

• X. Xing, E. R. Mohler III, C. Zhou, T. Durduran, G. M. Lech, Y. Shi, R. Wilensky, J. Moore, A. G. Yodh, G. Yu, Hemodynamic Changes in Diabetic Pig Muscle, in SVMB 18th Annual Meeting (Baltimore, MA, 2007)
• G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, S. J. Friedberg, A. G. Yodh, Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation During Clinical Prostate and Pleural Photodynamic Therapy, Proc. SPIE: on Biomedical Optics (San Jose, CA, 2007)
• G. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. Wang, J. M. Murphy, E. R. Mohler III, A. G. Yodh, Concurrent Diffuse Optical and MRI Measurement of Blood Flow in Human Skeletal Muscle, Proc. SPIE: on Biomedical Optics (San Jose, CA, 2007)
• X. Xing, E. R. Mohler III, C. Zhou, T. Durduran, G. M. Lech, Y. Shi, R. Wilensky, J. Moore, A. G. Yodh, G. Yu, Hemodynamic Changes in Diabetic Pig Muscle, Proc. SPIE: on Biomedical Optics (San Jose, CA, 2007)
• G. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, A. G. Yodh, Validation of Diffuse Correlation Spectroscopy for Muscle Blood Flow with Concurrent Arterial-Spin-Labeling Perfusion MRI, 54^th Annual Meeting of American College of Sports Medicine (ACSM) (New Orleans, LA, 2007)
• J. Im, S. Smith,, G. Yu, G. M. Lech, S. Nioka, A. G. Yodh, B. Chance, Impaired Skeletal Muscle Blood Flow, Mitochondrial Function and Exercise Capacity in Type II Diabetes with PAD: A Simultaneous NIRS and ³¹P-MRS Study, 54^th Annual Meeting of American College of Sports Medicine (ACSM) (New Orleans, LA, 2007)

• T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, J. A. Detre, Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position, International Stroke Conference, (San Francisco, CA 2007)

• G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, S. J. Friedberg, A. G. Yodh, Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation During Clinical Prostate and Pleural Photodynamic Therapy, 11^th World Congress of the Internation Photodynamic Association (IPA), (Shanghai, China, 2007)

• G. Yu, T. Durduran, C. Zhou, H.W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, 11^th World Congress of the Internation Photodynamic Association (IPA), (Shanghai, China, 2007)

-- 2006 --

· G. Yu, T. Durduran, C. Zhou, G. M. Lech, E. R. Mohler III, A. G. Yodh, Assessment of Muscle Vascular Disease with Diffuse Light, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

· G. Yu, T. Durduran, C. Zhou, J. C. Finlay, T. C. Zhu, T. M. Busch, S. B. Malkowicz, S. M. Hahn, A. G. Yodh, Real-Time Diffuse Optical Measurements of Hemodynamic Responese to PDT in Human Prostate, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

· G. Yu, T. Durduran, C. Zhou, G. M. Lech, E. R. Mohler III, A. G. Yodh, Diffuse Light Quantification of Blood Flow, Oxygenation and Metabolism in Human Skeletal Muscle, in American College of Sports Medicine (ACSM) (Denver, CO, 2006)

• G. Yu, T. F. Floyd, T. Durduran, C. Zhou, J. J., Wang, J. A. Detre, E. R. Mohler III, A. G. Yodh Concurrent Optical-MRI Measurement of Limb Blood Flow/Perfusion, in SVMB 17th Annual Meeting (Philadelphia, PA, June, 2006)

· G. Yu, Turgut Durduran, Chao Zhou, Jarod C. Finlay, Timothy C. Zhu, Theresa M. Busch, S. Bruce Malkowicz, Stephen M. Hahn, Arjun G. Yodh, Diffuse Optical Measurements of Tissue Blood Flow and Oxygenation during Interstitial Prostate PDT, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· G. Yu, T. Durduran, C. Zhou, G. Lech, E. R. Mohler III, A. G. Yodh, Assessment of Muscle Vascular Disease with Diffuse Light, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· T. Durduran, G. Yu, M. G. Burnett, C. Zhou, J. J. Wang, Q. Shah, S. Kasner, J. A. Detre, A. G. Yodh, J. H. Greenberg, Diffuse Optical Measurement of Cerebral Metabolic Rate of Oxygen In Adult Brain, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

· C. Zhou, T. Durduran, G. Yu, S. Eucker, S. Friess, R. Ichor, S. Margulies, A. G. Yodh, Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Head Trauma Injury, in World Congress on Medical Physics and Biomedical Engineering 2006 (Seoul, Korea, 2006)

· T. Durduran, C. Zhou, G. Yu, A. M. Hoang, K. Z. Tang, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurement of Local Cerebral Blood Flow, Blood Oxygenation and Metabolism During Cognitive Tasks, 12th Annual Meeting of the Organization for Human Brain Mapping (Florence, Italy, 2006)

· C. Zhou, T. Durduran, G. Yu, S. Eucker, S. Friess, R. Ichord, S. Margulies, A. G. Yodh, Real-Time Monitoring of Hemodynamic Changes in Neonatal Pig Brain with Head Trauma Injury, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· R. Choe, C. Zhou, T. Durduran, G. Yu, N. Shah, A. Durkin, A. Cerussi, B. J. Tromberg, A. G. Yodh, Neoadjuvant Chemotherapy Monitoring with Diffuse Optical Measurement of Blood Flow in Breast Tumors, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· Zhou C, Durduran T, Szabados T, Yu G, Choe R, Xing X, Greenberg JH, Durian, DJ and Yodh, AG, Noise Model for Laser Speckle Contrast Imaging, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· U. Sunar, C. Zhou, T. Durduran, G. Yu, A. G. Yodh, I. Lee, Ranpirnase Enhances Efficacy of Radiation on {A549} Human Lung Cancer Xenografts of Nude Mice Assessed by Diffuse Optical Spectroscopies, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· A. Sunar, H. Quon, J. Zhang, J. Du, T. Durduran, C. Zhou, G. Yu, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, A. G. Yodh, Changes in Optical Blood Flow and Oxygenation of Head and Neck Tumors During Chemo-Radiation Therapy, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· U. Sunar, S. Makonnen, H. W. Wang, T. Durduran, C. Zhou, G. Yu, I. Lee, A. G. Yodh, Non-Invasive, Continuous Monitoring of a Vascular Targeting Drug by Diffuse Optical Blood Flow and Blood Oxygenation Measurements, in OSA Biomedical Optics (Fort Lauderdale, FL, 2006)

· C. Zhou, T. Durduran, T. Szabados, O. Pascual, G. Yu, A. G. Yodh, P. G. Haydon, J. H. Greenberg, Optical Imaging of Cerebral Hemodynamic Response during Vibrissae Stimulation in Transgenic Mice Stroke Models, (Cortona, Italy, 2006)

-- 2005 --

· G. Yu, T. Durduran, C. Zhou, G. Lech, E. R. Mohler III, A. G. Yodh, Assessment of Muscle Vascular Disease with Diffuse Light, in 2005 Workshop on Investigation of Human Muscle Function In Vivo (Nashville, Tennessee, 2005)

· G. Yu, T. F. Floyd, J. M. Murphy, T. Durduran, C. Zhou, A. G. Yodh, Concurrent Optical-MRI Measurement of Limb Blood Flow/Perfusion, in 2005 Workshop on Investigation of Human Muscle Function In Vivo (Nashville, Tennessee, 2005)

· G. Yu, E. R. III Mohler, T. Durduran, C. Zhou, G. Lech, A. G. Yodh. Simultaneous Quantification of Pulmonary and Leg Muscle VO2 during Maximal Exercise in Humans, in 2005 Workshop on Investigation of Human Muscle Function In Vivo (Nashville, Tennessee, 2005)

· G. Yu, E. R. III Mohler, T. Durduran, C. Zhou, G. Lech, A. G. Yodh. Simultaneous Quantification of Pulmonary and Leg Muscle VO2 during Maximal Exercise in Humans, in Society For Vascular Medicine and Biology (Chicago, 2005)

• G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler III, A. G. Yodh, Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscles, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)
• G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

• T. Durduran, G. Yu, M. G. Burnett, C. Zhou, J. J. Wang, J. A. Detre, J. H. Greenberg, A. G. Yodh. Diffuse Optical Measurements of Cerebral Blood Flow, Oxygenation and Oxygen Metabolism in Adult Brain, in European Conferences on Biomedical Optics, OSA (Munich, Germany, 2005)

· T. Durduran, G. Yu, C. Zhou, D. Furuya, J. P. Culver, A. G. Yodh, J. H. Greenberg, Development of Diffuse Correlation Techniques for Non-Invasive Measurement of Cerebral Blood Flow and Metabolism in Rats, BRAIN 05, International Society of Cerebral Blood Flow and Metabolism (Amsterdam, NL, 2005)

· T. Durduran, G. Yu, M. G. Burnett, C. Zhou, J. J. Wang, J. A. Detre, A. G. Yodh, J. H. Greenberg, Diffuse Optical Measurement of Cerebral Metabolic Rate of Oxygen in Adult Brain, BRAIN 05, International Society of Cerebral Blood Flow and Metabolism (Amsterdam, NL, 2005)

• T. Durduran, G. Yu, C. Zhou, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh, Three Dimensional Imaging of Oxygen Metabolism in Rats During Cortical Spreading Depression, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)
• T. Durduran, G. Yu, M. G. Burnett, C. Zhou, J. J. Wang, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurement of Cerebral Oxygenation, Flow and Oxygen Metabolism in Adult Human Brain, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)
• C. Zhou, T. Durduran, G. Yu, A. G. Yodh, Optimization of 3D Blood Flow Imaging by Diffuse Correlation Tomography: Signal-To-Noise Analysis, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)
• T. Durduran, T. Shimazu, G. Yu, M. G. Burnett, C. Zhou, J. A. Detre, J. H. Greenberg, A. G. Yodh, Characterization of the Spatio-Temporal Behavior of Cerebral Blood Flow Using Laser Speckle Flowmetry during Electrical and Mechanical Stimulation of the Forepaw and Whiskers and during Transient Forebrain Ischemia, in Proc. SPIE: on Biomedical Optics (San Jose, CA, 2005)

· U. Sunar, H. Quan, J. Zhang, J. Du, T. Durduran, C. Zhou, G. Yu, A. Kilger, R. Lustig, L. Loevner, S. Nioka, A. G. Yodh, B. Chance, Monitoring of Radiation Therapy Response of Head and Neck Tumors by Non-invasive Optical Blood Flow Measurements, in European Conferences on Biomedical Optics, OSA (Munich, Germany, 2005)

-- 2004 --

· G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, A. G. Yodh, Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscles Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies, in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, 2004)

· G. Yu, T. Durduran, C. Zhou, H.W. Wang, M. Putt, A. G. Yodh, T. M. Busch, Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy, in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, 2004)

· G. Yu, T. Durduran, C. Zhou, F. Jarod, T. Zhu, S. J. Hahn, A. G. Yodh, Real-time Diffuse Optical Measurement of Hemodynamic Responses to PDT in Human Prostate, in the Institute For Medicine AND Engineering (IME) Interdisciplinary Research Symposium 2004 (University of Pennsylvania, Philadelphia, PA, 2004)

· G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy, in International Conference on Tumor Progression and Therapeutic Resistance (Philadelphia, PA, 2004)

• G. Yu, T. Durduran, C. Zhou, F. Jarod, T. C. Zhu, S. M. Hahn, A. G. Yodh, Real-time Diffuse Optical Measurement of Hemodynamic Responses to PDT in Human Prostate, in International Conference on Tumor Progression and Therapeutic Resistance (Philadelphia, PA, 2004)

• G. Yu, T. Durduran, C. Zhou, H.W. Wang, M. Putt, T. M. Busch, A. G. Yodh, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)
• G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler III, A. G. Yodh, Noninvasive Quantification of oxidative metabolism in Human Skeletal Muscle Using Hybrid Near-infrared Diffuse Optical Spectroscopies, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)

• G. Yu, T. Durduran, C. Zhou, H.W. Wang, M. Putt, A. G. Yodh, T. M. Busch, Prediction of Treatment Efficacy by Hemodynamic Responses to PDT in RIF Tumors, in 32^nd Annual Meeting of the American Society of Photobiology (ASP) (Seattle, WA, 2004)

• G. Yu, T. Durduran, G. Lech, C. Zhou, C. Britton, A. G. Yodh, Non-Invasive Measurements of Deep Tissue Hemodynamics in Human Skeletal Muscle, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)
• G. Yu, T. Durduran, C. Zhou, M. Putt, A. G. Yodh, T. M. Busch, Prediction of Treatment Efficacy by Blood Flow Responses to PDT in RIF Tumors, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)
• Turgut Durduran, G Yu, M G Burnett, C Zhou, D Furuya, J A Detre, J H Greenberg, A G Yodh, Spatio-temporal Quantification of Cerebral Blood Flow During Forepaw Stimulation of the Rat Using Laser Speckle Flowmetry, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)
• Turgut Durduran, G Yu, M G Burnett, C Zhou, J A Detre, J H Greenberg, A G Yodh, Hybrid Diffuse Optical Measurements of Oxygen Metabolism in Human Brain during Sensorimotor Stimulus, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

• C. Zhou, T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurements of Oxygen Metabolism in Human Brain during Sensorimotor Stimulus, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)
• C. Zhou, T. Durduran, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, 3D in-vivo Flow Imaging by Diffuse Correlation Tomography, in Fourth Inter-Institute Workshop on Optical Diagnostic Imaging from Bench to Bedside at NIH, (Bethesda, MA, 2004)

• M. G. Burnett, T. Durduran, G. Yu, C. Zhou, J. A. Detre, J. H. Greenberg, A. G. Yodh, A Novel Bedside Instrument for Non-invasive Measurement of Cerebral Hemodynamics: Development and Results of Human Testing During Cortical Sensorimotor Activation in Congress of Neurological Surgeons (San Francisco, CA, 2004)

• C. Zhou, T. Durduran, G. Yu, A. G. Yodh, Optimization of 3D Flow Imaging by Diffuse Correlation Tomography, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)
• R. Choe, T. Durduran, G. Yu, J. M. Nijland, B. Chance, A. G. Yodh, Nirmala Ramanujam, Transabdominal Near-infrared Fetal Brain Oximetry, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)
• M. G. Burnett, T. Durduran, G. Yu, C. Zhou, J. A. Detre, J. H. Greenberg, A. G. Yodh, A Novel Bedside Instrument for Non-invasive Measurement of Cerebral Hemodynamics: Development and Results of Human Testing During Cortical Sensorimotor Activation, in Congress of Neurological Surgeons Annual Meeting (San Franciso, CA, 2004)

• T. Shimazu, T. Durduran, M.G. Burnett, G. Yu, A.G. Yodh, J.A. Detre, J.H. Greenberg, Acute Recovery of Functional Activation Following Forebrain Ischemia in the Rat: A Laser Speckle Study, in Neuroscience (2004)

• U. Sunar, J. Zhang, J. Du, T. Durduran, C. Zhou, G. Yu, A. Kilger, H. Quon, R. Lustig, L. Loevner, S. Nioka, K. Pourrezaei, A.G. Yodh and B. Chance, Clinical Responses of Head & Neck Tumors to Radiation Therapy by NIR Spectroscopy, in OSA Technical Digest (Optical Society of American, Miami, FL, 2004)

-- 2003 --

• G. Yu, T. Durduran, G. Lech, B. Chance, A. G. Yodh, Noninvasive Hemodynamic Measurements during Exercise and Cuff-ischemia in Human Calf Muscle, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)
• G. Yu, T. Durduran, T. M. Busch, C. Zhou, A. G. Yodh, Hemodynamic Changes in RIF Tumors during and after PDT, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)
• G. Yu, T. Durduran, M. G. Burnett, J. A. Detre, J. H. Greenberg, A. G. Yodh, Diffuse Optical Measurements of Hemodynamics in Human Brain, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)
• G. Yu, T. Durduran, D. Furuya, J. H. Greenberg, A. G. Yodh, Oxygen Metabolism during Cortical Spreading Depression at Altered Ventilation States, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)

• G. Yu, T. Durduran, T. M. Busch, H. W. Wang, C. Zhou, H. M. Saunders, C. M. Sehgal, A. G. Yodh, Hemodynamics in RIF Tumors during and after PDT, in 9th World Congress of The International Photodynamic Association (Miyazaki, Japan, 2003)
• G. Yu, T. Durduran, D. Furuya, G. Lech, C. Zhou, B. Chance, J. H. Greenberg, A. G. Yodh, Hemodynamic Measurements in Rat Brain and Human Muscle Combining Diffuse Near-infrared Absorption and Correlation Spectroscopies, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)
• G. Yu, T. Durduran, T. M. Busch, H. W. Wang, C. Zhou, H. M. Saunders, C. M. Sehgal, A. G. Yodh, Non-invasive Monitoring Hemodynamic Responses in RIF Tumors during and after PDT, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)

• R. Choe, T. Durduran, G. Yu, M. J. Nijland, P. W. Nathanielsz, B. Chance, A. G. Yodh, N. Ramanujan, Non-invasive Cerebral Hemoglobin Oxygenation Quantification of Fetal Sheep under Hypoxic Stress In-utero using Frequency-domain Diffuse Optical Two-layer Model, in Engineering Conferences International (ECI) (Alberta, Canada, 2003)
• M. G. Burnett, T. Durduran, G. Yu, A. Cardenas, J. A. Detre, J. H. Greenberg, Characterization of the Activation-flow Coupling Response during Forepaw Stimulation in the Rat using Laser Speckle Contrast Imaging, in Brain03 and Brain PET03 (Alberta, Canada, 2003)

• T. Durduran, G. Yu, G. Lech, C. Zhou, B. Chance, A. G. Yodh, Noninvasive and Simulataneous Measurements of Tissue Oxygenation and Blood Flow during Exercise and Cuff-Ischemia in Human Calf Muscle, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V, (San Jose, CA, 2003)

• T. Durduran, G. Yu, M. G. Burnett, D. Furuya, J. A. Detre, J. H. Greenberg, A. G. Yodh, Measuring Oxygen Metabolism during Cortical Spreading Depression at Altered Carbonation States, in SPIE Photonics West (San Jose, CA, 2003)

• C. Zhou, T. Durduran, G. Yu, A. G. Yodh, Optimizing Image Reconstruction of Tissue Blood Flow For Diffuse Correlation Spectroscopy, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)
• R. Choe, T. Durduran, G. Yu, J. M. Nijland, P. W. Nathanielsz, B. Chance, A. G. Yodh, N. Ramanujam, Non-invasive Cerebral Hemoglobin Oxygenation Quantification of Fetalmsheep under Hypoxic Stress In-utero Using Frequency-domain Diffuse Optical Two-layer Model, in Proc. SPIE: Optical Tomography and Spectroscopy of Tissue V (San Jose, CA, 2003)

-- 2002 & 2001--

• G. Yu, T. Durduran, D. Furuyab, J. H. Greenberg, and A. G. Yodh, Hemodynamic Measurements in Rat Brain Combining Diffuse Near-infrared Absorption and Correlation Spectroscopies, in Proc. SPIE: Progress in Biomedical Optics and Imaging (Shanghai, China, 2002)
• G. Yu, T. Durduran, D. Furuyab, J. H. Greenberg, and A. G. Yodh, Diffuse Optical Multiplexing System in Frequency Domain for in vivo Monitoring of Rapid Hemodynamics, in Twenty-First Southern Biomedical Engineering Conference: Biomedical Engineering: Recent Developments (Washington DC, MA, 2002)
• G. Yu, T. Durduran, D. Furuya, R. Choe, J. H. Greenberg, A. G. Yodh, Frequency Domain Diffuse Optical Multiplexing System for Rapid Hemodynamics, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)
• T. Durduran, G. Yu, J. P. Culver, C. Cheung, D. Furuya, J. H. Greenberg, A. G. Yodh, Hemodynamics of Cortical Spreading Depression and Forepaw Stimulation, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)
• T. Durduran, G. Yu, D. Furuya, R. Choe, J. P. Culver, C. Cheung, J. H. Greenberg, A. G. Yodh, Effects of Duration, Hypoxia and Hypercapnia on Rat Brain Hemodynamics during Forepaw Stimulation, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)
• T. Durduran, G. Yu, J. P. Culver, C. Cheung, D. Furuya, J. H. Greenberg, A. G. Yodh, Hemodynamics of Cortical Spreading Depression and Forepaw Stimulation, in OSA Technical Digest (Optical Society of American, Miami, FL, 2002)
• T. Durduran, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, Measuring Oxygen Metabolism during Somatosensory Cortex Activation by Forepaw Stimulation in Rat Brains under Different Physiological Conditions, in ISOTT 2002 (Manchester, UK, 2002)
• T. Durduran, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, In Vivo Measurements of Brain Hemodynamics in Rat Brain using Diffuse Optical Tomography and Diffuse Correlation Spectroscopy, in American Physical Society (Indianapolis, IN, 2002)
• T. Durduran, G. Yu, D. Furuya, R. Choe, J. P. Culver, C. Cheung, J. H. Greenberg, A. G. Yodh, In Vivo Measurements of Cerebral Hemodynamics in Rats using Diffuse Optical Tomography and Diffuse Correlation Spectroscopy: Instrumentation & Results, in Gordon Research Conference (New Hampshire, 2002)

· J. H. Greenberg, D. Furuya, T. Durduran, G. Yu, J. A. Detre, A. G. Yodh, The Effect of Carbon Dioxide on the Hemodynamic and Metabolic Response to Cortical Spreading Depression, in Program No. 581.9, Abstract Viewer/Itinerary Planner (Washington DC: Society for Neuroscience, 2002)

· T. Durduran, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, In Vivo Measurements of Rat Brain hemodynamics using Diffuse Optical Tomography and Diffuse Correlation Spectroscopy, in Chalk-Talk Series, Institute of Medicine and Engineering, University of Pennsylvania (Philadelphia, PA, 2001)